Alli diet pills do not work (Orlistat)? An evidence-based review

Losing weight can be very difficult.

Some studies show that 85% of people not using conventional methods for weight loss ( 1 ).

This causes many people, other methods such as diet pills, to search.

Alli is a pill, such as diet, but is a pharmaceutical drug, rather than an herbal supplement.

This drug limits the amount of fat in the diet of our body to absorb that reduction in caloric intake ^[1] and leads to weight loss ^[2] .

This is a detailed review of Alli diet pills: what they are, how they work, and whether they are right for you.

What is Alli (Orlistat)?

Alli is the over-the-counter version of a weight loss drug orlistat ^[3] .

The only version called Xenical prescription that a higher dose. Alli diet pills that while Xenical pills contain 60 mg orlistat 120 mg.

This drug was approved by the FDA in 1999. As a rule, long-term for the treatment of obesity, prescribed along with a low-fat, low-calorie diet.

Conclusion: Alli is the over-the-counter version of orlistat, a drug used to treat obesity. It is also by prescription as Xenical available.

Thats how it works?

Alli prevents the body absorb dietary fat.

In particular, an enzyme in the intestine blocked called lipase ^[4] .

The lipase is essential for the digestion of fats we eat. It helps break down fats into free fatty acids that can be recognized by the body.

Without this enzyme, exceeds the digestion of fats in the diet and is then excreted from the body.

As lipase inhibitors, it has been found that the absorption of dietary fat by 30% (reduction 2 ).

Because dietary fat is high in calories, which leads to fewer calories, they are processed in the body, which can lead to weight loss.

Conclusion: Alli stops the digestion of fats and block absorbs 30% of dietary fat from. This leads to an overall reduction in caloric intake.

Alli will help you lose small amounts of weight

Several large studies in humans have done to orlistat, the active compound in the Alli diet pills.

The most famous is the XENDOS Swedish study that included obese 3305 and lasted four years ( 3 ).

There were two study groups. 120 mg of orlistat was taken three times a day, while the other group received a placebo.

All participants were invited to eat 800 calories less per day and limiting dietary fat to 30% of calories. You will also be asked to go for a walk every day.

This table shows the changes in weight in both groups of more than four years ( 3 ):

During the first year the average weight loss in the orlistat-treated group was 23.3 pounds (10,6 kg), while the placebo group lost only 13.6 pounds (6.2 kg).

As the chart shows, there was a lot of weight gain in both groups during the remaining three years. Orlistat patients ended up losing 12.8 pounds (5.8 kg), compared to 6.6 pounds (3.0 kg) to those who received placebo.

The study is Orlistat can be combined with diet and exercise, so to lose weight almost twice diet and exercise.

Other studies

After an evaluation study, weight loss 12 months will average adult under Orlistat about 7.5 pounds (3,4 kg) over placebo ( 4 ).

This corresponds to 3.1% of the initial weight, which are not particularly impressive. It also seems that the weight slowly again after the first year of treatment.

Interestingly, one study showed that drug-free low carb diet ^[5] was as effective as two orlistat and a low fat diet combined ( 5 ).

Conclusion: Alli / Xenical is a moderately effective weight loss drug, with the average weight loss after 12 months, 3.4 kg (7.5 pounds) more than placebo.

Alli diet pills do have other health benefits?

It has probably also brought many other health benefits because of the effects of weight loss in conjunction.

• Reduce the risk of type 2 diabetes: study In XENDOS, with four years Orlistat decreases the risk of developing type 2 diabetes by 37% ( 3 ).
• Lowering blood pressure: Studies show that Alli may in modest reductions in blood pressure (episode 6 , 7 ).
• Full Reduction and LDL cholesterol: Studies show that Alli can positively influence cholesterol levels ( 6 , 8 ).

Conclusion: Prolonged use Alli can reduce the risk of type 2 diabetes and protecting against heart disease.

Side effects, dosage and how to use

Alli diet pills have some well-documented side effects not listed ( 9 ).

And blocks the absorption of fat, the presence of undigested fat in the gut can cause digestive symptoms such as abdominal pain, diarrhea and flatulence.

Some people also fecal incontinence and oily loose stools.

More use Alli may affect the absorption of fat-soluble nutrients such as vitamins A, D, E and K.

For this reason, we recommend a multivitamin and treatment.

It can also interfere with the absorption of some drugs, and some cases of hepatic failure and renal toxicity reported.

The people who have some type of drug or medical condition should consult their doctor before taking diet pills Alli.

Based on limited data on the long-term, most guidelines recommend that Alli is not used continuously for more than 24 months.

The optimal dose of the study is used, is 120 mg three times daily.

You can Alli diet pills (60 mg) on sale at Amazon , but if you want to receive the most effective dose of 120 mg, then you should get a prescription for Xenical by your doctor.
^[6]

Conclusion: Alli diet pills have many side effects. You can cause digestive problems and nutrient deficiencies, can also interfere with some medications. The dose tested was 120 mg three times daily.

You should try Alli?

Alli diet pills are one of the few aid weight loss that actually work to some degree. However, the effects are not as impressive as would most people.

At best, you may be able to lose a little weight, but only when combined with diet and exercise.

Moreover, the positive effects on weight loss against the negative effects of digestive problems and possible nutrient deficiencies should be weighed.

Not to mention, you need to eat a low-calorie diet low in fat, which is very pleasant for many people.

If you really want to lose weight and keep it off, and then want to eat more protein ^[7] and fewer carbohydrates ^[8] is a much more efficient and sustainable approach.

Decisive for the diet pills on the basis of evidence and supplements, read this article: 12 pills and supplements weight loss of public opinion ^[9] .

Credentials

1. ^{^} calorie intake (authoritynutrition.com)
2. ^{^} weight loss (authoritynutrition.com)
3. ^{^} Orlistat (en.wikipedia.org)
4. ^{^} lipase (en.wikipedia.org)
5. ^{^} diet low in carbohydrates (authoritynutrition.com)
6. ^{^} Amazon (www.amazon.com)
7. ^{^} more protein (authoritynutrition.com)
8. ^{^} fewer carbohydrates (authoritynutrition.com)
9. ^{^} 12 pills and supplements weight loss of public opinion (authoritynutrition.com)